Scientific research supporting the claim that Omega-3 Fatty Acids help Support
a Healthy Brain.
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Gamoh, S., M. Hashimoto, K. Sugioka, S. Hossain, N.
Hata, Y. Misawa, and S. Masumura. "Chronic
administration of docosahexaenoic acid improves
reference memory-related learning ability in young
rats." Neurosci 93:237-241 (1999).
Jones, C. R., T. Aria, and S. I. Rapoport. "Evidence
for the involvement of docosahexaenoic acid in
cholinergic simulated signal transduction at the
synapse." J Neurochem Res 22:663-670 (1997).
Katzman, R., and J. E. Jackson. "Alzheimer disease:
Basic and clinical advances." J Am Geriatrics Soc
Kodas E., Page G., Zimmer L., Vancassel S.,
Guilloteau D., Durand G., Chalon S. "Neither the
density nor function of striatal dopamine
transporters were influenced by chronic n-3
polyunsaturated fatty acid deficiency in rodents.”
Neurosci Lett 321(1-2):95-9 (2002).
Kyle, D. J., E. Schaefer, G. Patton, and A. Beiser.
"Low serum docosahexaenoic acid is a significant
risk factor for Alzheimer's dementia." Lipids
Lauritzen, I., N. Blondeau, C. Heurteaux, C. Widmann,
G. Romey, and M. Lazdunski. "Polyunsaturated fatty
acids are potent neuroprotectors." EMBO J
Burgress, J. R., L. Stevens, and L. Peck.
"Long-chain polyunsaturated fatty acids in children with attention-deficit
Am J Clin Nutr 71:327S-330S (2000).
Connor, W. E., M. Neuringer, and D. S. Lin. "Dietary
effects on brain fatty acid composition: The reversibility of n-3 fatty acids
deficiency and turnover of docosahexaenoic acid in the brain erythrocytes and
plasma of rhesus monkeys." J Lipid Res 31:237-247 (1990).
Connor, W. E., M. Neuringer, and S. Reisbick.
"Essential fatty acids: Importance of n-3 fatty acids in the retina and brain."
Ntr Rev 50:21-29 (1992).
Conquer, J. A., M. C. Tierney, J. Zecevic, W.J.
Bettger, and R.H. Fisher. "Fatty acid analysis of blood plasma of patients with
Alzheimer's disease, other types of dementia, and cognitive impairment."
Lipids 35:1305-1312 (2000).
Fenton W. ., Dickerson F., Boronow J., Hibbeln J.
R., Knable M. “A placebo-controlled trial of omega-3 fatty acid (ethyl
eicosapentaenoic acid) supplementation for residual symptoms and cognitive
impairment in schizophrenia.” Am J Psychiatry 158(12):2071-4 (2001).
Lauritzen, L., H. S. Hansen, M. H. Jorgensen, and K.
F. Michaelsen. "The essentiality of long-chain n-3
fatty acids in relation to development and function
of the brain and retina." Prog Lipid Res
Marangell L B, Martinez J M, Zboyan H A, Kertz B,
Kim H F, Puryear L J. “A double-blind,
placebo-controlled study of the omega-3 fatty acid
docosahexaenoic acid in the treatment of major
depression.” Mood Disorders Center, Department of
Psychiatry, Baylor College of Medicine, Houston, TX,
Schiefermeier M., Yavin E. “n-3 Deficient and
docosahexaenoic acid-enriched diets during critical
periods of the developing prenatal rat brain.” J
Lipid Res 43(1):124-31 (2002).
Sonderberg, M., C. Edlund, K. Kristensson, and G.
Dallner. "Fatty acid composition of brain
phospholipids in aging and Alzheimer's disease."
Lipids 26:421-423 (1991).
Stevens, L. J., and J. Burgess. "Omega-3 fatty acids
in boys with behavior, learning, and health
problems." Physiol Behav 59:915-920 (1996).
Voigt, R. G., A. M. Llorente, C. L. Jensen, J. K.
Fraley, M.C. Berretta, and W. C. Heird. "A
randomized, double-blind, placebo-controlled trial
of docosahexaenoic acid supplementation in children
with attention-deficit/hyperactivity disorder." J
Pediatr 139:189-196 (2001).
Vance, H. E., R. B. Campenot, and D. E. Vance. "The
synthesis and transport of lipids for axonal growth
and nerve regeneration." Biochim Biophys Acta
Yeh, Y. Y., M. F. Gehman, and S. M. Yeh. "Maternal
dietary fish oil enriches docosahexaenoate levels in
brain subcellular fractions of offspring." J
Neurosci Res 35:218-226 (1993).
Yehuda, S., S. Rabinovitz, R.L. Carasso, and D.I.
Mostofsky. "Essential fatty acid preparation
improves Alzheimer's patients' quality of life."
Int J Neurosci 87:141-149 (1996).
Willatts, P., J. S. Forsyth, M. K. DiModugno, S.
Varma, and M. Colvin. “Effect of long-chain
polyunsaturated fatty acids in infant formula on
problem solving at 10 months of age.” Lancet
Stevens, L. J., S. S. Zentall, J. L. Deck, M. L.
Abate, B. A. Watkins, S. A. Lipp, and J. R. Burgess.
"Essential fatty acid metabolism in boys with
attention-deficit hyperactivity disorder." Am J
Clin Nutr 62:761-768 (1995).
Stordy, B. J. "Benefit of docosahexaenoic acid
supplements to dark adaption in dyslexics."
Lancet 346:385 (1995).
Terano, T., S. Fujishiro, T. Ban, K. Yamamoto, T.
Tanaka, Y. Noguchi, Y. Tamura, K. Yazawa, and T.
Hirayama. "Docosahexaenoic acid supplementation
improves moderately severe dementia from thromboitc
cerebrovascular diseases. Lipids 34:S345-S346